Comparative Evaluation of Effect of Dentin on the Ph of Chlorhexidine Based Intracanal Irrigants

The aims of endodontic treatment in cases of apical periodontitis are to reduce as much as possible the number of microorganisms inside the root canal system and to inactivate toxins produced by them. Chlorhexidine has a wide spectrum of antimicrobial activity and is known for its property of substansivity. It is also known that dentin exerts a buffering effect under wide pH variations, and may be responsible for decreasing the antimicrobial activity of drugs inside the root canal. The objectives of this study were to assess the pH of different solutions of chlorhexidine gluconate in presence of dentin at various time interval. Dentin powder was obtained from extracted human teeth and added as 1.8% to the volume of the solutions. A pH meter was used at five different moments to assess pH in medium: immediately after preparation and after 24 h, and 7, 14. Results were analyzed by one way ANOVA test. Statistically significant differences were observed in the every group and least change in pH was observed in 20% chlorhexidine gluconate at all time intervals when compared to the other groups(P < 0.05).